Hepatoprotective and Antioxidant Effects of Ecbolium viride, Gendarussa vulgaris and Sphaeranthus amaranthoides in NASH Induced Hepatotoxicity in Albino Wister Rats

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dc.contributor.authorRamasamy, Sakthivel
dc.date.accessioned2025-07-24T11:44:15Z
dc.date.available2025-07-24T11:44:15Z
dc.date.issued2020
dc.description.abstractNon-alcoholic steatohepatitis (NASH) caused due to over-nutrition, decreased physical activity with disproportionate high-fat food intake, obesity, type II diabetes mellitus (T2DM), and the metabolic syndrome characterized by steatosis, lobular inflammation and progressive pericellular fibrosis. This hepatic disease cannot be remedied by chemicals its addition may lead to complication. Hence herbal drug is the possible remedy. The hepatoprotective effect of Ecbolium viride, Gendarussa vulgaris and Sphaeranthus amaranthoides were monitored by estimating the Triglycerides(TG),Total cholesterol(TC),Low density lipoprotein(LDL), High density lipoprotein (HDL), Aspartate transaminases (AST), Alanine transaminases (ALT), Alkaline phospatases (ALP), and Lactate dehydrogenases (LDH).Plant extracts singly or in combination at a dose of 2g/kg significantly prevented the increase in serum level inliver. Theantioxidant enzymes following D- Galactosamine and diet induced hepatoxicity in albino rats was reversed by plant extracts.
dc.identifier.issn2347-6648
dc.identifier.urihttps://ds.dmiseu.org/handle/123456789/72
dc.language.isoen
dc.publisherParishodh Journal
dc.subjectEcbolium viride
dc.subjectGendarussa vulgaris
dc.subjectSphaeranthus amaranthoides
dc.subjectNASH
dc.subjectHepatoprotection
dc.subjectD-Galactosamine.
dc.titleHepatoprotective and Antioxidant Effects of Ecbolium viride, Gendarussa vulgaris and Sphaeranthus amaranthoides in NASH Induced Hepatotoxicity in Albino Wister Rats
dc.typeArticle

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