Dominic Ravichandran2025-12-152025-12-152015-06https://ds.dmiseu.org/handle/123456789/508Breast cancer is the most prevalent form of cancer in women world over. MCF-7 cells are useful for in vitro breast cancer studies because the cell line has retained several ideal characteristics particular to the mammary epithelium. These include the ability for MCF-7 cells to process estrogens, in the form of estuarial, via estrogens receptors in the cell cytoplasm. This makes the MCF-7 cell line an estrogens receptor (ER) positive control cell line. In breast cancer cells containing oestrogen receptors both oestrogens and growth factors can stimulate proliferation, invasion and the secretion of a number of proteins.